We found that miR-302b post-transcriptionally down-regulated ErbB

We found that miR-302b post-transcriptionally down-regulated ErbB4 expression in vitro. We also concluded that miR-302b inhibited proliferation by inducing apoptosis and repressed the invasive ability of ESCC cells, and an ErbB4-mediated pathway may be involved in this function. Acknowledgments

This work was supported by the National Natural Science Foundation of China (81302055), the Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT: 1171) and Key Sci-tech Research Project “13115” of Shaanxi Province (2010ZDKG-50). References 1. Parkin DM, Bray FI, Devesa SS: Cancer burden in the year 2000. The global picture. Eur J Cancer 2001, 37:S4-S66.Selleck MI-503 PubMedCrossRef 2. Allgayer H, Fulda S: PHA-848125 in vitro An introduction to molecular targeted therapy of cancer. Adv Med Sci 2008, 53:130–138.PubMedCrossRef 3. Tew WP, Kelsen DP, Ilson DH: Targeted therapies for esophageal

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