Reporting of short- and long-term safety and efficacy outcomes in

Reporting of short- and long-term safety and efficacy outcomes in the medical literature is strongly encouraged. Data for these procedures should also be reported to a program’s AZD9291 molecular weight center of excellence database. Any marketing or advertisement for this procedure should include a statement to the effect that this is an investigational procedure. The aim of this study is to review current publications on LGCP especially reported complications and results on excess weight loss (EWL). No other published reviews on Gastric Plication or Laparoscopic Greater Curvature Plication were found during research of the literature, which makes this an original study. 3. Method Online literature research and current library-based peer-reviewed journals review. Online search engines employed are as follows: Medline/PubMed, Google Scholar, and SciVerse.

Key words are as follows: Gastric Plication, Laparoscopic Gastric Plication, Laparoscopic Greater Curvature Plication, (LGCP), and Total Vertical Gastric Plication, (TVGP). Peer-reviewed journals: Surgical Endoscopy, Obesity Surgery, Surgery for Obesity and Related Diseases, Journal of Laparoendoscopic and Advanced Surgical Techniques, and Bariatric Times. Languages of the published data were: English and Spanish. Timeframe searched was January 2000�CDecember 2011. 4. Contemporary Literature Review There are currently a total of 11 (eleven) articles in the published literature on LGCP as a standalone surgical technique. Publications referring to greater curvature plication in combination with another technique, such as Laparoscopic Gastric Banding with Greater Curvature Plication, were excluded.

One variation of LGCP is Anterior Plication (AP), a technique proposed by Brethauer et al. involving plication of the anterior wall of the stomach without mobilization of the greater curvature. This study was included as there was also a group of patients undergoing LGCP, and also because omission of mobilization of the grater curvature could be an interesting idea, further reducing the risk of bleeding. A study by Khazzaka and Sarkis on a group of obese patients with gastroesophageal reflux disease (GERD) was also included as it shows the potential of gastric plication in treating these specific patients. Research revealed 1 (one) preclinical study and 8 (eight) prospective studies. 5. Preclinical Studies As was the case with LSG, LGCP was first performed to patients and subsequently studied in animal models. Data from Dr Talebpour’s original animal trials have not been published. Menchaca et al. [8] performed a study on hound dogs, comparing the efficacy of 3 different methods for fastening Cilengitide the plicated gastric wall, namely, T-tags, sutures, and staples (Level of evidence II-1).

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