This review is timely given the increasing interest in early intervention strategies and new opportunities to identify patients early in the pathogenesis of RA.
Recent findings
Despite the growing literature demonstrating
a link between anticitrullinated protein antibodies, synovitis, genetic and environmental risk selleck chemicals llc factors such as smoking and RA, there are no studies that have evaluated the effect of modifying environmental risk factors in late preclinical RA. This article describes several studies that have evaluated the ability of pharmacologic interventions to modify outcomes in patients at risk for RA.
Summary
The prevention of RA in at-risk populations is feasible; however, this will necessitate novel efforts to identify patients very early in disease development to examine the effectiveness and cost of preventive interventions.”
“Objective: The purpose of this report is to extend the current understanding of patient satisfaction by examining expectations of a sample
of breast cancer patients and concordance with their medical oncologists about the content of consultations and the importance of consultation items.
Methods: Three hundred and ninety-five female early stage breast cancer patients of 56 oncologists participated. Patients and oncologists completed a matched questionnaire measuring (a) met expectations, (b) concordance over content and item importance, and (c) satisfaction.
Results: Overall patient satisfaction was extremely high (x = 91/100%) although expectations were not met at the stated level desired. Patients and physicians URMC-099 disagreed
over what was conveyed and received. Higher overall satisfaction was predicted by levels of met expectations (unstandardized beta = 0.69, p = 0.008, SE = 0.26) Selleck ERK 抑制剂 and concordance over (a) content (unstandardized beta = 1.09, p = 0.002, SE = 0.34) and (b) importance (unstandardized beta = -0.78, p = 0.006, SE 0.28).
Conclusion: Although patient expectations were not well met and physician-patient discord was high about the content of consultations and the importance of consultation items, patients reported high levels of satisfaction. Expectation fulfillment and levels of concordance predicted satisfaction. Copyright (c) 2008 John Wiley & Sons, Ltd.”
“Purpose of review
Patients with osteoporosis suffer from the morbidity and mortality associated with resultant fractures. The number of persons at risk for fractures is increasing as the US population ages. This review addresses preventive strategies that can be used to decrease the risk of minimal trauma fractures.
Recent findings
Dietary and lifestyle modifications and screening to identify individuals most likely to benefit from pharmacologic interventions, important components of osteoporosis prevention, will be discussed.