Objective: The purpose of this study was to estimate the associat

Objective: The purpose of this study was to estimate the association of whole-grain intake (g/d) and risk see more of incident hypertension in a large prospective cohort of men.

Design: The Health Professionals Follow-Up Study is a prospective cohort consisting of 51,529 male health professionals ranging in age from 40 to 75 y at enrollment in 1986. Baseline and updated measurement of whole-grain intake as well as important covariates were measured, and 31,684 participants without known hypertension, cancer, stroke, or coronary

heart disease were followed prospectively for 18 y through 2004 for onset of hypertension.

Results: A total of 9227 cases of incident hypertension were reported over the 18 y of follow-up. In multivariate-adjusted BVD-523 ic50 analyses, whole-grain intake was inversely associated with risk of hypertension, with a relative risk (RR) of 0.81 (95% CI: 0.75-0.87) in the highest compared with the lowest quintile (P for trend < 0.0001).

In the multivariate model, total bran was inversely associated with hypertension, with a relative risk (RR) of 0.85 (95% CI: 0.78, 0.92) in the highest compared with the lowest quintile (P for trend: 0.002).

Conclusions: In summary, we found an independent inverse association between intake of whole grains and incident hypertension in men. Bran may play an important role in this association. These findings have implications for future dietary guidelines and prevention of hypertension. Am J Clin Nutr 2009;90:493-8.”
“This paper deals with aging phenomena in polymers under electric stress. In particular, we focus our efforts on the development of a novel theoretical S63845 method accounting for the discharge process partial discharge) in well known defects present in polymers, which are essentially tiny air gaps embedded in a polymeric matrix. Such defects are believed to act as trigger points for the partial discharges and their induced aging process.

The model accounts for the amplitude as well as the energy distribution of the electrons during their motion, particularly at the time in which they impact on the polymer surface. The knowledge of the number of generated electrons and of their energy distributions is fundamental to evaluate the amount of damage caused by an avalanche on the polymer-void interface and get novel insights of the basic phenomena underlying the relevant aging processes. The calculation of such quantities would require generally the combined solution of the Boltzmann equation in the energy and space/time domains. The proposed method simplifies the problem, taking into account only the main phenomena involved in the process and provides a partial discharge (PD) model virtually free of adjustable parameters.

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