Marjolin’s ulcer is classified into acute and chronic subgroups. Acute scar carcinoma, which is rarely seen, occurs sooner than one year after injury.7 Acute Marjolin’s ulcer is more often basal cell carcinoma and is associated with more superficial burn scars.5 The latency period is inversely proportional to the patient’s

age at the time of burn injury.1 The mean average period of chronic carcinoma development, more frequent type, is 35.5 years.7 We herein present an otherwise healthy 54-year-old Jewish man, who developed Marjolin’s ulcer only 6 weeks after his burn injury. The patient had superficial scald burn injuries, about 3% of the body surface area, on his right foot and right hand, which Inhibitors,research,lifescience,medical healed with conservative management after 3 weeks. Two weeks later, a 10-mm exophytic fragile nodule, which

bled with minor manipulation, was noted in the dorsal aspect of his right hand. The nodule was excised completely, the wound was closed Inhibitors,research,lifescience,medical primarily, and the tissue was sent for histopathologic evaluations. The histopathology of the lesion was well-differentiated squamous cell carcinoma (figures 1 and ​and2).2). Consequently, re-excision with a 10-mm margin was done, and full-thickness skin graft was performed. The confirmation of complete excision was done by Inhibitors,research,lifescience,medical the pathologist. Now 2 years on since the excision, the patient is systemically well, with no evidence of local recurrence. Figure 1 Ulceration with invasion of malignant keratinizing squamous cells through the dermis (H&E ×100). Figure 2 Nests of well-differentiated squamous cells, producing keratin

pearls (H&E ×100). Marjolin’s ulcer is a potentially aggressive malignant tumor, which has a typically long latency period. Although Inhibitors,research,lifescience,medical acute Marjolin’s ulcer (latent period less than one year) is very uncommon, Inhibitors,research,lifescience,medical we believe that the appearance of any nodules or ulceration on a healed burn area at any age or site and with any latent period should be excised and evaluated histologically. Conflict of Interest: None declared.
Inguinal bladder hernia is a rare clinical condition. Indeed, only 1-3% of all inguinal hernias are reported to involve the bladder.1 The incidence may reach 10% among obese men older than 50 years of age, however.2,3 Massive inguinoscrotal bladder hernia, also known as scrotal cystocele, is a Megestrol Acetate very rare condition.1 In this condition, one portion of the bladder or a diverticulum forms all or a part of the scrotal hernia. Even more uncommon is inguinal bladder hernia descending into the scrotum. Small bladder hernia is usually asymptomatic, whereas large scrotal bladder hernia presents with intermittent scrotal or inguinal bulging and lower urinary tract symptoms and occasionally patients complain of double voiding. Diagnosis is find more confirmed with cystography and ultrasonography. Surgical repair of hernia is the best choice for treatment.