Incidentally detected neoplastic pathologies need further post-operative evaluation and management. The objective of this study is to describe the pathology of gallbladder after cholecystectomy for symptomatic gallstone disease to find out the value of routine pathological assessment. Methods: Pathology reports of all cholecystectomies done for symptomatic gallstone disease, in the university surgical unit of Sirtuin activator the national hospital of Sri Lanka over 5 years were analyzed. Results: There were 220 pathology reports to include in the study. 32% and 68% were males and females respectively. 31% was

females between 30 to 50 years of age. Chronic cholecystitis, acute on chronic cholecystitis and xanthogranulomatous cholecystitis were found in 89.5%, 5% and 2% patients respectively. Normal gallbladder, gangrenous cholecystitis, follicular cholecystitis were seen in three patients. Two patients had chronic cholecystitis with gastric metaplasia and one patient had chronic cholecystitis with focal high grade dysplasia. Adenocarcinoma of the gallbladder was encountered in 2 patients (0.9%) and they were in T1 and T2 stage of the disease. Conclusion: Chronic cholecystitis due to gallstone is the commonest pathology identified in patients with symptomatic gallstone disease. Incidental finding of neoplastic pathologies (malignant or premalignant)

of the Ruxolitinib solubility dmso gallbladder is a rarity, but it is detected at an early stage of the disease which carry a good prognosis following further surgical interventions. Key Word(s): 1. gall bladder; 2. histopathology Presenting Author: JUN KYU LEE Additional Authors: IN WOONG HAN, KYOUNG HEE HONG Corresponding Author: JUN KYU LEE Affiliations: Dongguk University Ilsan Hospital, Dongguk University Ilsan Hospital Objective: Postcholecystectomy syndrome (PCS) is characterized by abdominal pain following gallbladder removal. The purpose of this trial is to determine whether Rowachol will be useful in the prevention of PCS and in symptoms improvement after laparoscopic cholecystectomy (LC). Methods: From

2012 to 2013, this prospective, randomized, single 上海皓元 blind, placebo-controlled study had balanced random assignment Rowachol and placebo in Dongguk University Ilsan Hospital, and Chung-Ang University Hospital. A total of 138 patients, with various gallbladder diseases after LC, were enrolled and randomized. Rowachol or placebo 100 mg three times daily was given to each group of patients for 3 months. Outcomes were assessed in visit over 3 months after surgery with right upper quadrant (RUQ) pain on European Organization for Research and Treatment of Cancer QLQ-C30. Results: There are no differences in aspect of demographics, preoperative clinical findings, and surgical findings between each group. Incidence of PCS in placebo group (n = 9, 14.3%) was higher than that in Rowachol group (n = 3, 4.7%) with statistically marginal significance (p = 0.089).