Accurate population-based data are needed on the incidence of Barrett’s esophagus. Since Barrett’s is believed to be the major risk factor for the development of esophageal adenocarcinoma. Risk factors for Barrett’s esophagus include advanced age (age
> 40), male sex, white race, symptoms of reflux, and obesity. Barrett’s esophagus is present in 10%–20% of patients with gastro NVP-LDE225 esophageal reflux disease (GERD) and has also been detected in patients who deny classic GERD symptoms and are undergoing endoscopy for other indications. Methods: We conducted adescriptive study involving all patients with Barrett’s esophagus (BE) in Cipto Mangunkusumo Hospital in Jakarta during the period from 2008 through 2012, using data from the Anatomical Pathology Registry and the Endoscopic Centre in Cipto Mangunkusumo Hospital. Results: There were 5782 patients who underwent endoscopic from 2008–2012 and we identified 959 patients as esofagitis,
4.7% was suspected for BE. From the histopathological result, among those who are suspected BE, 29.7% was confirmed BE, while those who are not suspected BE, 5.04% was positive for BE. Endoscopy has sensitivity 23% and specificity 96.3% in detecting BE with positive predictive value 29% and negative predictive value 95%. Those who were diagnosed with barrets esophagus, 6.7% classified as low grade dysplasia, 28.8% EX 527 manufacturer with non dysplasia, and 1.7% with indeterminate-grade dysplasia, while the rest were only classified as barrets esophagus. In this study, BE was found more common in male and in the range of age of 51–60 years old learn more (37%). The most common presenting symptoms among patients diagnosed with barrets esophagus was dyspepsia, only 5% the presenting symptom was GERD. Conclusion: in Cipto Mangunkusumo hospital, those patients whose endoscopic apperances were be suspect has higher rate of
pative histophaology result. Key Word(s): 1. BE; 2. GERD; 3. endoscopy; Presenting Author: MURDANI ABDULLAH Additional Authors: HAYATUN NUFUS Corresponding Author: MURDANI ABDULLAH Affiliations: Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine University of Indonesia, CiptoMangunkusumo Hospital, Jakarta, Indonesia Objective: Colorectal cancer is the fourth leading cause of cancer-related mortality worldwide. Early detection of colorectal cancer is necessary in term of increasing survival. Immunochemical fecal occult blood test (I-FOBT) is one of simple and inexpensive screening modality that can be used widely. No data has been available yet regarding of usage of I-FOBT in Indonesia. The aim of this study was to determine prevalence and diagnostic study of I-FOBT as a screening for colorectal cancer in Indonesia asymptomatic population. Methods: A cross sectional study was conducted in asymptomatic population living near five public health service in Depok, East Java, Indonesia. This study was performed during January – March 2012.