001). The lactate: pyruvate ratio was not higher in the RE group than in the CE group before endotoxemia but increased significantly during endotoxemia
in the RE group (P = 0.04).
Conclusion: A well-nourished condition before prolonged endotoxemia results in a better ability to adapt to endotoxin-induced metabolic deterioration of arginine-nitric oxide metabolism than does reduced caloric intake before endotoxemia. Am J Clin Nutr 2010; 91: 992-1001.”
“The effect of carbon codoping on boron distribution in implanted silicon has been investigated at the atomic scale using atom probe tomography. Whereas small boron-enriched clusters a few nm in size, containing about 2.4 at. % of boron atoms, are clearly visible in
carbon-free B-implanted silicon after annealing at 800 degrees C for 30 min, no boron clustering is evidenced if C is coimplanted in the sample. C coimplantation is known to reduce the Y 27632 electrical deactivation of boron, but, in addition, this suggests that C addition induces a larger fraction of mobile boron near the peak of the B profile. (C) 2011 American Institute of Physics. [doi:10.1063/1.3533416]“
“We have determined the structure of the core capsid of an unusual variant of hepatitis B virus, genotype G (HBV/G) at 14 A resolution, using cryo-electron microscopy. The structure reveals surface features not present in the prototype HBV/A genotype. HBV/G is novel in that it has a unique 36- bp insertion downstream of the core gene start codon. This results in a twelve amino acid insertion at the N-terminal end of the core protein, and two stop codons in the precore region that prevent the expression of HBeAg. AZD9291 Protein Tyrosine Kinase inhibitor HBV/G IWR-1-endo in vitro replication in patients is associated with co-infection with another genotype of HBV, suggesting that HBV/G may have reduced replication efficiency in vivo. We localized the N-terminal insertion in HBV/G and show that it forms two additional masses
on the core surface adjacent to each of the dimer-spikes and have modelled the structure of the additional residues within this density. We show that the position of the insertion would not interfere with translocation of nucleic acids through the pores to the core interior compartment. However, the insertion may partially obscure several residues on the core surface that are known to play a role in envelopment and secretion of virions, or that could affect structural rearrangements that may trigger envelopment after DNA second-strand synthesis.”
“Nonpercolated composites based on polyurethane (PU) filled with low concentrations copper (Cu) powders of varying sizes were studied as electrostrictive materials for mechanical energy harvesting. The dispersion of the fillers within the polymeric matrix was investigated by scanning electron microscopy, and results showed a relatively homogeneous dispersion for the microsized fillers and the existence of agglomerates for their nanosized counterparts.