common mode of activity or negative result path) through a structured fat of evidence approach. But, whenever such mechanistic data are not offered, grouping could be carried out using a common adverse outcome. Toxicokinetic data can also be ideal for grouping, particularly when kcalorie burning information is readily available for a course of compounds and common toxicologically appropriate metabolites tend to be shared. In inclusion, prioritisation techniques provide methods to determine low-priority chemical compounds and lower the amount of chemical substances in an evaluation team. Prioritisation practices consist of combined risk-based methods, risk-based methods for single chemicals and exposure-driven approaches. Situation researches happen offered to illustrate the program of hazard-driven requirements additionally the use of prioritisation means of grouping of chemical substances in assessment groups. Strategies for future work tend to be discussed.Technical data for exposure evaluation of food enzymes nutritional exposure is part of the total assessment of meals enzymes. To be able to develop meals process-based visibility designs, a number of different ML intermediate input data are expected in tandem with technical transformation elements. This allows for a mixture of use levels with food usage information, that are typically reported as used. The employment amounts are expressed as total natural solids/kg raw materials. For every food process, EFSA identified a summary of meals groups and collated technical transformation elements. To make sure consistent application of FoodEx food categories and technical conversion elements into the read more evaluation of food chemical dossiers, stakeholders had been consulted via available calls-for-data. Suggestions ended up being analysed. This document reports the consolidated input parameters for each meals process. Regular revisions have been made on a yearly basis since 2018, because additional process-specific parameters had been created. The consolidated feedback information being accustomed calculate nutritional publicity through the assessment of food enzyme programs. As well as publishing the feedback parameters, process-specific calculators of the food enzyme consumption designs (FEIM) have also been created on such basis as summary statistics. These calculators being deposited at https//zenodo.org/ for open access.The food enzyme rennet paste containing chymosin (EC 3.4.23.4), pepsin A (EC 3.4.23.1) and triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is ready through the abomasum of suckling goats, lambs and calves by Caglificio Clerici S.p.A. The meals chemical is intended to be found in milk processing for mozzarella cheese manufacturing. As no problems arise from the animal supply of the meals chemical, from the manufacture, and on the basis of the reputation for safe usage and consumption, the Panel views that toxicological data are not required and no publicity evaluation was needed. On the basis of literature information, the Panel considers that, under the intended conditions of use, the threat of allergic sensitisation and elicitation reactions by dietary visibility could not be omitted, but the possibility is known as to be reasonable. Based on the information offered, the Panel concludes that this meals enzyme doesn’t produce protection issues under the desired conditions of use.The applicant Syngenta Crop Protection AG provided a request towards the genetic fate mapping skilled nationwide expert in Belgium to judge the confirmatory data that have been identified for metalaxyl-M within the framework of the MRL review under Article 43 and Article 12 of legislation (EC) No 396/2005 as perhaps not available. To deal with the information gaps new data regarding analytical options for enforcement (validation information for hops and cocoa beans, ILV for fat) and several residue tests data supporting adjusted spaces for metalaxyl-M on oranges, pears, broccoli, cauliflower, natural herbs and edible flowers, soya beans and cocoa beans had been posted. Two data spaces regarding analytical methods for administration (validation data for hops and cocoa beans, ILV for fat) were considered satisfactorily dealt with. However, the data space on validation of the performance of this removal, hydrolysis and derivatisation actions within the recommended analytical means for administration of deposits in livestock was not addressed. The data gap for residue trials encouraging authorisations of metalaxyl-M was partly addressed. The data gap for residue studies encouraging authorisations of metalaxyl was not addressed. This new information supplied may require a revision of this present MRLs for a couple of commodities of plant and animal source. Further danger administration considerations are needed.Following a request through the European Commission, EFSA had been asked to deliver a scientific viewpoint from the safety and efficacy of l-lysine monohydrochloride (l-lysine HCl) and l-lysine sulfate produced by Corynebacterium glutamicum (C. glutamicum) CGMCC 14498 as a nutritional feed additive for several animal species. The active substance is l-lysine and it is stated in two variations (monohydrochloride or sulfate). The production stress C. glutamicum CGMCC 14498 as well as its recombinant DNA were not recognized within the final services and products.